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STRAP, also a WD containing protein, interacts with both TGF receptor types, as well as Smads 2, 3 and 7 24, 25. STRAP is thought to stabilize the association of inhibitory Smad7 with the receptor, which inhibits TGF dependent transcription, probably by interfering with Smad2/3 binding to the receptors or by recruiting a receptor phosphatase (see below). Another protein called TRAP 1 binds only to the activated TGF receptors and inhibits TGF induced signaling 26.

The use of the adsorbent styrenedivinylbenzene reverse phase sulfonated (SDB RPD) Empore disk in a chemcatcher type passive sampler is routinely applied in Australia when monitoring herbicides in aquatic environments. One key challenge in the use of passive samplers is mitigating the potentially confounding effects of varying flow conditions on chemical uptake by the passive sampler. Performance reference compounds (PRCs) may be applied to correct sampling rates (Rs) for site specific changed in flow and temperature however evidence suggests the use of PRCs is unreliable when applied to adsorbent passive samplers.

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